Studies in Sulphonamides -Part V

  • G. S Saharia University of Delhi, Delhi
  • H. R. Sharma University of Delhi, Delhi
Keywords: E coli, Sulphonamidobenzeneazo, Dibenzoylmethanes


Five substituted dibenzoylmethanes, 1-(p-chlorophenyl)-1-(p-bromophenyl)-, 1-(p-methylphenyl)-, 1-(p-methoxyphenyl)-, and 1-(p-biphenyl)-3-phenyl propane-1:3-diones are coupled with diazotised sulphanilamide, sulphacetamide, N/sup 1/ phenyl-, N/sup 1/p-chlorophenyl-, N/sup 1/p-methylphenyl-, N/sup 1/ p-methoxyphenyl-, N/sup 1/ pyrimidyl-, N/sup 1/ guanidyl-, N/sup 1/-4:6-dimethylpyrimidyl-and N/sup 1/r-pyridylulphanilamides in presence of sodium acetate. All these forty one substituted sulphonamidobenzeneazo 1:3-diketones are crystallised and screened in vitro for their antibacterial properties and some of these are found to be highly active against S. aureus and E. coli.
How to Cite
SahariaG., & SharmaH. (2014). Studies in Sulphonamides -Part V. Defence Science Journal, 22(2), 135-138.
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