Studies in Heterocyclic Compounds-Part XXXIII : Synthesis and in vitro screening of some 1,3-diaryl-5-(arylazo/N-substituted p-sulphamylbenzeneazo) dihydro-2-thioxo-4,6 (1H, 5H)-pyrimidinedioes

  • S. C. Nigam University of Delhi, Delhi
  • G. S. Saharia University of Delhi, Delhi
  • H. R. Sharma University of Delhi, Delhi
DOI: https://doi.org/10.14429/dsj.31.6332
Keywords: Diazotised sample, Sulphonamide bases

Abstract

1-Phenyl-3-(p-methoxyphenyl)- and 1,3-di(p-methoxyphenyl) dihydro-2-thioxo-4,6 (1H, 5H)-pyrimidinediones have been synthesised and coupled with different diazotised simple and sulphonamide bases to furnish the corresponding 5-(arylazo/N- substituted p-sulphamylbenezeneazo)dihydro-2-thioxo-4, 6(1H, 5H)-pyrimidinediones. On in vitro screening these were found to exhibit considerable activity against a number of micro-organisms.

Author Biographies

S. C. Nigam, University of Delhi, Delhi
Department of Chemistry, University of Delhi, Delhi-110 007
G. S. Saharia, University of Delhi, Delhi
Department of Chemistry, University of Delhi, Delhi-110 007
H. R. Sharma, University of Delhi, Delhi
Department of Chemistry, University of Delhi, Delhi-110 007
Published
2014-02-18
How to Cite
Nigam, S., Saharia, G., & Sharma, H. (2014). Studies in Heterocyclic Compounds-Part XXXIII : Synthesis and in vitro screening of some 1,3-diaryl-5-(arylazo/N-substituted p-sulphamylbenzeneazo) dihydro-2-thioxo-4,6 (1H, 5H)-pyrimidinedioes. Defence Science Journal, 31(1), 15-22. https://doi.org/10.14429/dsj.31.6332
Issue
Vol 31 No 1
Section
General Papers
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