Effect of Diisopropyl Phosphorofluoridate in Some Aspects of Carbohydrate Metabolism
Keywords: Glycogenolysis, Hyperglycemia, Glycolytic rate, LDH activity
AbstractAn acute dose of DFP equivalent to 50 per cent of the LD50 cause glycogenolysis and hyperglycemia in male albino rats. The hyperglycemic effect can atleast be partially suppressed by the administration of insulin. Under sub-acute dose equivalent to 5 per cent of the LD50, there is glycogenolysis but no change is blood glucose. The action of DFP on carbohydrate metabolism seems to be mediated through adrenal gland. DFP also increases the glycolytic rate, suppresses the LDH activity and is hepatotoxic.
How to Cite
Chatterjee, A., & Kaveeshwar, U. (2013). Effect of Diisopropyl Phosphorofluoridate in Some Aspects of Carbohydrate Metabolism. Defence Science Journal, 41(2), 143-147. https://doi.org/10.14429/dsj.41.4420
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