Studies in Sulphonamides-Part XI

  • H. C. Mutreja University of Delhi, Delhi
  • G. S. Saharia University of Delhi, Delhi
  • H. R. Sharma University of Delhi, Delhi
DOI: https://doi.org/10.14429/dsj.29.6520
Keywords: Coli, Pyocyanea, Sodium Acetate

Abstract

In this paper four 1-methyl-3-arylpropane-1, 3-diones, 1methy1-3-(3'4'-dichlorophenyl)-methyl1-3-(2-chloro-5'-methylphenyl)-1-methyl-3-(a-naphthyl)-, 1-methyl1-3-(5'6'7'8'-tetrahydro-naphth-2'-yl)propane-1,3-diones have been synthesised and coupled with different diazotised sulphonamide bases in presence of sodium acetate to give the corresponding 1-methyl-3-aryl-2- (N-substituted p-sulphamylbenezeneazo) propane-1, 3-diones. These azo compounds have been tested in vitro for their antibacterial properties against S. aureus, E.coli and p. pyocyanea and were found to possess considerable activity.

Author Biographies

H. C. Mutreja, University of Delhi, Delhi
Department of Chemistry, University of Delhi-110 007
G. S. Saharia, University of Delhi, Delhi
Department of Chemistry, University of Delhi-110 007
H. R. Sharma, University of Delhi, Delhi
Department of Chemistry, University of Delhi-110 007
Published
2014-02-25
How to Cite
MutrejaH., SahariaG., & SharmaH. (2014). Studies in Sulphonamides-Part XI. Defence Science Journal, 29(4), 181-186. https://doi.org/10.14429/dsj.29.6520
Issue
Vol 29 No 4
Section
General Papers
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