Preparation of Oxime HI-6 (Dichloride and Dimethanesulphonate)ŒAntidote against Nerve Agents
Keywords: HI-6, acetylcholinesterase, nerve agent, quaternary salts, oxime, reactivator, antidote, organophosphate
AbstractBecause of the threat of misuse of nerve agents as terroristic weapons by the terrorists, animmediate need is felt for the preparation of antidotes on large-scale basis. HI-6 (dichloride anddimethanesulphonate) salt are the most promising acetylcholinesterase reactivators used ascausal antidotes in nerve agents intoxication. In this study, rapid and large-scale preparationof oxime HI-6, the most promising reactivator has been described.
How to Cite
Kuca, K., Stodulka, P., Hrabinova, M., Hanusova, P., Jun, D., & Dolezal, B. (2008). Preparation of Oxime HI-6 (Dichloride and Dimethanesulphonate)ŒAntidote against Nerve Agents. Defence Science Journal, 58(3), 399-404. https://doi.org/10.14429/dsj.58.1660
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