Synthesis of p-(Di-n-propylsulphamyl) Benzoic Acid

Authors

  • S. K. Shukla Defence Science Laboratory, Delhi
  • Govind Rai Chaudhry Defence Science Laboratory, Delhi

DOI:

https://doi.org/10.14429/dsj.18.7458

Keywords:

Penicillin, Benemid Probenecid, Chronic Gouty Arthritis

Abstract

A process for the synthesis of p-carboxybenzene sulphonylchloride by oxidation of toluene-p-sulphonylchloride as well as toluene-p-sulphonic acid has been developed. p-carboxybenzene sulphonylchloride on condensation with di-n-propylamine yield p-(di-n-propylsulphamyl) -benzoic acid, an uricusuric agent employed in chronic gouty arthritis and used as an antiuric adjuvant known in trade as "Benemid, Probenecid".

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Published

2014-05-23

How to Cite

Shukla, S. K., & Chaudhry, G. R. (2014). Synthesis of p-(Di-n-propylsulphamyl) Benzoic Acid. Defence Science Journal, 18(4), 239–240. https://doi.org/10.14429/dsj.18.7458

Issue

Vol. 18 No. 4

Section

Research Papers

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