Synthesis of p-(Di-n-propylsulphamyl) Benzoic Acid
Keywords: Penicillin, Benemid Probenecid, Chronic Gouty Arthritis
AbstractA process for the synthesis of p-carboxybenzene sulphonylchloride by oxidation of toluene-p-sulphonylchloride as well as toluene-p-sulphonic acid has been developed. p-carboxybenzene sulphonylchloride on condensation with di-n-propylamine yield p-(di-n-propylsulphamyl) -benzoic acid, an uricusuric agent employed in chronic gouty arthritis and used as an antiuric adjuvant known in trade as "Benemid, Probenecid".
How to Cite
Shukla, S., & Chaudhry, G. (2014). Synthesis of p-(Di-n-propylsulphamyl) Benzoic Acid. Defence Science Journal, 18(4), 239-240. https://doi.org/10.14429/dsj.18.7458
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