Oxidative Degradation of Fentanyl in Aqueous Solutions of Peroxides and Hypochlorites

  • Lihong Qi Institute of Chemical Defence, Beijing
  • Zhenxing Cheng Institute of Chemical Defence, Beijing
  • Guomin Zuo Institute of Chemical Defence, Beijing
  • Shanmao Li Institute of Chemical Defence, Beijing
  • Qiping Fan Institute of Chemical Defence, Beijing
Keywords: Fentanyl, degradation pathway, countering terrorism, addictive drugs, incapacitants

Abstract

Fentanyl widely used in clinics as practices is potentially utilised as an incapacitant in countering terrorism and its analogues would be used as an addictive drug, so the degradation of these compounds need to be investigated for protecting environment and human health. In this work, the degradation of fentanyl was examined in a series of oxidant aqueous solutions. Meanwhile, the degradation pathways of fentanyl in the oxidant solution were discussed according to all products identified by GC/MS and LC/MS.

Defence Science Journal, 2011, 61(1), pp.30-35, DOI:http://dx.doi.org/10.14429/dsj.61.68

Author Biographies

Lihong Qi, Institute of Chemical Defence, Beijing

Dr Lihong Qi obtained her MTech and PhD from the Institute of Chemical Defence, and is currently working at the institute as Asst Prof. She has published more than 10 research papers in both national and international journals.

Zhenxing Cheng, Institute of Chemical Defence, Beijing

Prof Zhenxing Cheng obtained his MTech and PhD from Paris VI University. At present, he is working as a Professor in the institute of Chemical Defence. He has published more than 60 research papers in both national and international journals. He has successfully completed more than 10 Govt-funded projects in the areas of defence technology against chemical warfare agents.

Guomin Zuo, Institute of Chemical Defence, Beijing

Dr Guomin Zuo obtained his MTech and PhD from the Institute of Chemical Defence, and is currently working here as Associate Professor. He has published more than 70 research papers in both national and international journals. He has successfully completed 2 Govt-funded projects in the areas of decontamination and sensing technology against chemical warfare agents.

Shanmao Li, Institute of Chemical Defence, Beijing

Prof Shanmao Li obtained his MTech from the Institute of Chemical Defence, and is currently working at the institute as Professor. He has published more than 50 research papers in both national and international journals.

Qiping Fan, Institute of Chemical Defence, Beijing

Mr Qiping Fan obtained his MTech from the Institute of Chemical Defense, and is currently working here as Asst Professor. He has published more than 20 research papers in both national and  international journals.

Published
2010-12-30
How to Cite
QiL., ChengZ., ZuoG., LiS., & FanQ. (2010). Oxidative Degradation of Fentanyl in Aqueous Solutions of Peroxides and Hypochlorites. Defence Science Journal, 61(1), 30-35. https://doi.org/10.14429/dsj.61.68
Section
Research Papers