A Note on Periodic Variations in Serum Cholesterol Serum Lecithin Cholesterol Acyl Transferase Activity and FaecalSterol and Bile Acid Excretion in the Rat Fed Different Levels of Dietary Protein

Abstract

Effects of three different levels of dietary protein (12,20 and 42%) on periodic variations in the serum cholesterol concentration, serum LCAT activity and faecal excretion of bile acids in rats fed hydpercholesteremic diet were investigated. Serum free cholesterol concentration and serum LCAT activity showed minor variations with time in rats ingesting concentration increased progressively but serum LCAT activity showed increase only at the end of 32 days in rats ingesting 20% protein diets. Average daily faecal excretion of bile acids per rat during different periods was lower in animals consuming 12% protein than those consuming higher levels of dietary protein.