Quinolines and Related Compounds as Potential Antimalarials

Abstract

Various 4-and 8-aminoquinoline derivatives having different substituents in the side chain and in the nucleus have been discussed in respect of their antimalarial activity and tolerance dosages. The effect of the incorporation of different moieties e.g. piperazine, piperidine and quinoline itself has also been highlighted. Certain quinoline quinones and benzoquinones as effective antimalarial agents have also been described.