Studies on Potential Pesticides-Part XIV : Synthesis and Biological Activities of some new Thiosemicarbazide and Triazole Derivatives

Abstract

Some new N-[5-(substituted phenoxymethyl)-1,3,4-oxadiazoly1-2-thioacetyl]-N-aryl-thiosemicarbazides have been synthesised by the condensation of appropriate hydrazine with aryliosothiocyanates. Cyclisation of these thiosemicarbazides in alkaline medium gives 3-[5-(substituted phenoxymethyl)-1,3,4-oxadiazolyl-2-thioacetyl]-4-aryl-5-mercapto-1,2,4-triazoles. All these compounds have been evaluated for their antibacterial properties and some of these have been screened for their anti fungal activity and AChE inhibition.