Drug/Xenobiotic-Metabolism, Disposition and Toxicity in Malnutrition

Authors

  • Kamala Krishnaswamy National Institute of Nutrition, Hyderabad

DOI:

https://doi.org/10.14429/dsj.37.5898

Keywords:

Bio transformation, Protein binding distribution

Abstract

The role of malnutrition and diet in general on bioprocess, which govern the fate of drug/xenobiotic in the body only just beginning to be understood. Absorption, protein binding distribution, bio-transformation and renal elimination of xenobiotics/drugs are all affected by altered states of nutrition. As such, evaluation of nutritional status is highly relevant prior to prolonged drug thereby especially with drugs having narrow safety margin.

Author Biography

Kamala Krishnaswamy, National Institute of Nutrition, Hyderabad

National Institute of Nutrition, Hyderabad-500 007

Downloads

Published

2014-01-15

How to Cite

Krishnaswamy, K. (2014). Drug/Xenobiotic-Metabolism, Disposition and Toxicity in Malnutrition. Defence Science Journal, 37(2), 133–142. https://doi.org/10.14429/dsj.37.5898

Issue

Section

General Papers