Radioimmunotargeting : Some Recent Advances

Abstract

Several new aspects of radioimmunotargeting for neoplastic lesions are reviewed in this paper. These include the use of single domain antibody, oncogene-coded protein and other intracellular targets so as to obtain pancarcinoma reactivity, newer methods of linking /sup 99m/Tc to antibodies for radioimmunoscintigraphy. The selection of candidate radionuclides for radioimmunotherapy, particularly the possible use of radiosilver and radiogold, and the strategies of enhanced tumour targeting were also reviewed.