View the PDF document Morphometric Studies of Cytological Specimens in Breast Carcinoma using Computerised Image Analysis System .

  • V. C. Padaki Defence Bioengineering & Electromedical Laboratory, Bangalore
  • K. S. Hegde Defence Bioengineering & Electromedical Laboratory, Bangalore
  • B. V. Ramesh Defence Bioengineering & Electromedical Laboratory, Bangalore
  • S. R. Sumathi Defence Bioengineering & Electromedical Laboratory, Bangalore
  • D. Hazarika Kidwai Memoria Institute of Oncology, Bangalore.
  • Prashantha Kumar Kidwai Memoria Institute of Oncology, Bangalore
  • C. V. Verghese Kidwai Memoria Institute of Oncology, Bangalore
Keywords: Image analysis, Radical mastectomy, Computerised interactive morphometry

Abstract

The value of nuclear parameters were determined using interactive computer image analysis system on 100 preoperative FNAC smears of breast lesion were radical mastectomy was performed subsequently. Twenty cases of benign lesion were taken as control. The lymph node status was correlated with the nuclear and nucleolar variables. It is found that few nuclear parameters have good discriminatory power. Computerised interactive morphometry proved to be far superior to eye-piece measurements with respect to accuracy, reproducibility and time taken for parameter estimation which leads to the determination of better prognostic indicator.

Author Biographies

V. C. Padaki, Defence Bioengineering & Electromedical Laboratory, Bangalore
Dr.V.C.Padaki received MSc (Physics) from Bangalore University , in 1975 and received PhD in Solidstate Physics from Indian Institute of Science, in 1981. Currently he is working as a Scientist at DEBEL, Bangalore. He is a member of Indian Group of international Society for Stereology. He has a number of publications to his credit. His research interests include non destructive testing, image processing and pattern recognition, medical imaging and quantitative cytology .
K. S. Hegde, Defence Bioengineering & Electromedical Laboratory, Bangalore
Dr KS Hegde received PhD in Physiology in 1988 from the University of Delhi. Since 1972, when he joined DRDO, he has been working in the fields of environmental and neurophysiology. At present he is working as a Scientist in Human Engineering and Biomedical Division of DEBEL, Bangalore.' He has several publications to his credit. He is a Life member of the Association of Physiologists and Pharmacologists of India. His current interests include
quantitative cytology and development of microclimatics cooling systems against high degree of thermal stress.
B. V. Ramesh, Defence Bioengineering & Electromedical Laboratory, Bangalore
Mr. BV Ramesh received MSc (Electronics) from Bangalore University, in 1980and is presently working as a Scientist at DEBEL, Bangalore. He is also persuing PhD at the Indian Institute 'of Science , Bangalore. He is a member of the Indian Group of International Society for Stereology. He has a number of publications to his credit. His research interests include quantitative cytology , medical imaging, image processing and pattern recognition , and operating systems.
S. R. Sumathi, Defence Bioengineering & Electromedical Laboratory, Bangalore
Defence Bioengineering and Electromedicala Laboratory Bangalore.
D. Hazarika, Kidwai Memoria Institute of Oncology, Bangalore.
Dr D Hazarika received MBBS from Dibrugarh University in 1978 and MD (Pathology) from PGI, Chandigarh, in 1983. Presently he is the Professor and Head, Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore. He has a number of publications to his credit. His research interests include quantitative and diagnostic cytology, and tumor pathology.
Prashantha Kumar, Kidwai Memoria Institute of Oncology, Bangalore
Mr Prasbaotha Kumar received MSc (Zoology) from Bangalore University, in 1987. He has specialised in the field of animal cytogenetics: He is working at Kidwai Memorial Institute of Oncology, Bangalore, since 1990, where he is currently persuing PhD in Oncopathology.
C. V. Verghese, Kidwai Memoria Institute of Oncology, Bangalore
Kidwai Memoria Institute of Oncology, Bangalore.
Published
2013-01-01
How to Cite
PadakiV., HegdeK., RameshB., SumathiS., HazarikaD., KumarP., & VergheseC. (2013). View the PDF document Morphometric Studies of Cytological Specimens in Breast Carcinoma using Computerised Image Analysis System . Defence Science Journal, 43(3), 229-233. https://doi.org/10.14429/dsj.43.4226
Section
Special Issue Papers

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