The Epigallocatechin Gallate Pharmacological Benefits and Bioavailability  A Review

Kunal Verma; Mansi .; Parul Sharma; Shobhit Kumar

doi:10.14429/dlsj.8.19108

Kunal Verma Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut–250 005, Uttar Pradesh, India https://orcid.org/0009-0002-7480-3634
Mansi . Food Science and Nutrition, Banasthali Vidyapith, Rajasthan–304 022, India https://orcid.org/0009-0002-4953-5017
Parul Sharma Food Science and Nutrition, Banasthali Vidyapith, Rajasthan–304 022, India https://orcid.org/0000-0001-8957-9431
Shobhit Kumar Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut–250 005, Uttar Pradesh, India https://orcid.org/0000-0001-9384-8219

DOI: https://doi.org/10.14429/dlsj.8.19108

Keywords: phytoconstituents, Reactive oxygen species, Soy protein hydrolysates, catechin, Nanoparticle

Abstract

The compound Epigallocatechin gallate (EGCG) a catechin is a major polyphenol found in green tea. This
polyphenolic compound is linked with several health benefits. The potential health benefits include antioxidant effects, cancer chemoprevention, improving cardiovascular health, aiding in weight loss, and protecting from skin damage caused by ionizing radiation, and others. It is prone to decreased stability, lower bioavailability, and lower absorption rate due to various environmental, processing, formulation, and gastrointestinal circumstances of the human body, and is being extensively researched for improvement in functional meals. Enhanced thermogenesis (heat production), enhanced fat oxidation, greater muscular glucose absorption, decreased hepatic fat content, and increased faecal fat excretion are further advantages. The purpose of this review is to highlight the pharmacological benefits of Epigallocatechin-3-gallate and to express the potential of EGCG and the necessity of further research on this therapeutic compound to expand its use in various food industries.