Development and Standardisation of a Method for Inflicting Frostbite Injury in Rats and Formulation of Essential Oil in Treatment of Frostbite
DOI:
https://doi.org/10.14429/dlsj.5.15606Keywords:
Frostbite device, Formulation, Wound contraction, Vascular injuryAbstract
Frostbite is a cold induced injury which occurs due to exposure of a particular site of body to sub-zero temperature. One of the primary reasons for lack of proper studies about the underlying mechanism of frostbite injury is due to non-availability of any reliable animal model and method for inflicting frostbite. In our current research, a device was designed and standardised to inflict frostbite wound in wistar rat. A formulation comprising different combination of essential oils was also developed and its activity was assessed and found effective in the treatment of frostbite wound.
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Published
2020-04-08
How to Cite
Joshi, K., Goyary, D., Mazumder, B., Kishor, S., Dey, P., Bhutia, Y. D., Karmakar, S., Chattopadhyay, P., & Dwivedi, S. K. (2020). Development and Standardisation of a Method for Inflicting Frostbite Injury in Rats and Formulation of Essential Oil in Treatment of Frostbite. Defence Life Science Journal, 5(2), 103–108. https://doi.org/10.14429/dlsj.5.15606
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