Evaluation of Antibacterial Potential of Daldinia concentrica from North Eastern Region of India
Morphological, bio-chemical and antibacterial potential of an ascomycetous fungus, Daldinia concentrica, was evaluated. It was collected from dead, decaying log of Mimusops elengi tree and isolated by plating in potato dextrose medium. Macroscopic and microscopic features of the stromata were studied. The crude methanol extract of the stromata (30 mg/ml) exhibited significant antibacterial activity against Escherichia coli (MTCC-40), Pseudomonas aeruginosa (MTCC-7093), Klebsiella pneumoniae (MTCC-661), Enterobacter aerogenes (MTCC-111) and Gram positive bacteria Staphylococcus aureus (MTCC-7443), Bacillus subtilis (MTCC-121). Bacillus subtilis was the most sensitive organism to the methanol extract of this fungus with 41.33 mm zone of inhibition. Gas Chromatographic–Mass Spectral Analysis of stromatal methanol extract revealed the presence of 19 compounds. The present investigation indicated the potential antibacterial activity of native D. concentrica, which could be useful for pharmaceutical application.
where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India