A Hypothetical Tool for Integrated Omics, Drugs and Clinical Stem Cell Data Analysis
Keywords: Integrated system analysis, Omics-drugs-disease-clinical databases, Tissue engineering, Radiation injury
AbstractUnderstanding the molecular basis of stem cell (SC) function is essential to regenerate damaged tissue due to various types of injuries and pathologies. However, there are bottlenecks that prevent the use of Stem cell in the treatment of wide range of diseases. Complete information regarding the control of gene expression in Stem cell is necessary to understand the regulation of Stem cell fates such as self-renewal, differentiation, migration/ homing and apoptosis. However, in the absence of multi-functional, single window tool for the analysis of various omics and drugs data related to Stem cell, the knowledge consolidation is missing to fully harness its potential. A tool which can integrate various databases, analysis software and gives a probable solution for Stem cell mediated regeneration of tissues using available therapeutic options would likely to help in reducing morbidity and mortality associated with various pathologies. This subsumes omics based repurposing of drugs for Stem cell guided tissue regeneration, which will be a boon for clinicians to treat various debilitating diseases/ malfunctions.
How to Cite
Verma, Y., & Gangenahalli, G. (2017). A Hypothetical Tool for Integrated Omics, Drugs and Clinical Stem Cell Data Analysis. Defence Life Science Journal, 2(3), 354-357. https://doi.org/10.14429/dlsj.2.11673
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