| || Structures Related to Morphine Synthesis of alpha 2 OH 2 Methyl 5 Propyl 9 Ethyl 6 7 Benzomorphan Part 1
Author : Joshi, Bhuwan C. ;Ramachandran, Reena
Source : Defence Science Journal ; Vol:20(4) ; 1970 ; pp 233-236
Subject : 54 Chemistry
Keywords : Benzomorphan ;Methyl;Phosphoric acid
Abstract : A three step synthesis of 2-methyl-5-methyl-9-ethyl-6, 7-benzomorphan from 3-ethyl-4-propyl pyridine was effected and only the a-form could be obtained through phosphoric acid cyclisation. This a-form of benzomorphan was converted to a-2-methyl-2-hydroxy-5-propyl-9-ethyl-6, 7-benzomorphan in three steps again. Infrared spectra of the base confirmed the presence of a-form.