| || Studies on Potential Pesticides Part XIV : Synthesis and Biological Activities of Some New Thiosemicarbazide and Triazole Derivatives
Author : Garg, Madhuri ;Sengupta, Anil K.
Source : Defence Science Journal ; Vol:31(2) ; 1981 ; pp 91-96
Subject : 54 Chemistry;547 Organic Chemistry
Keywords : AChE inhibition ;Anti fungal activity
Abstract : Some new N-[5-(substituted phenoxymethyl)-1,3,4-oxadiazolyl-2-thioacetyl]-N-aryl-thiosemicarbazides have been synthesised by the condensation of appropriate hydrazine with aryliosothiocyanates. Cyclisation of these thiosemicarbazides in alkaline medium gives 3-[5-(substituted phenoxymethyl)-1,3,4-oxadiazolyl-2-thioacetyl]-4-aryl-5-mercapto-1,2,4-triazoles. All these compounds have been evaluated for their antibacterial properties and some of these have been screened for their anti fungal activity and AChE inhibition.