| || Cardiovascular Response to High Altitude Hypoxia
Author : Manchanda, S.C
Source : Defence Science Journal ; Vol:34(4) ; 1984 ; pp 345-353
Subject : 61 Medical Sciences;612 Physiology
Keywords : High Altitude Hypoxia;Hypercapnia;Cardiovascular
Abstract : Normal and abnormal cardiovascular response to high altitude(HA) hypoxia were studied in 98 healthy subjects and in 15 patients with HA pulmonary oedema(HAPO) and acute mountain sickness(AMS) at an altitude of 3,658m. The healthy sea(SL) residents showed marked blood volume changes during the first week with pulmonary hypotension and depression of left ventricular(LV)performance and physical work capacity(PWC) indicating a better adaptation with normal left atrial pressures but the exact mechanism of this condition is still not clear. AMS subjects showed no circulatory that AMS may be caused by relative hyposensitiveness of the respiratory centre to hypoxia or hypercapnia.