 | Mohan, Chandra |
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 | Studies in Sulphonamides Part IX
Author : Mohan, Chandra;Saharia, G.S.;Sharma, H.R.
Source : Defence Science Journal ; Vol:25(3) ; 1975 ; pp 97-100
Subject : 577 Biochemistry;579 MicroBiology;61 Medical Sciences
Keywords : Sulphonamides
Abstract : Four differently substituted benzoylacetones, viz., 1-(4'-methylpheny1)-, 1-(4'-ethylpheny1)-, 1-(4'-methoxyphenyI)-, and 1-(4'-ethoxypheny1)-3-methy1 propane-1,3-diones have been synthesised and coupled with fourteen different diazotised sulphonamide bases. All the resulting sulphonamidobenzeneazo derivatives when subjected to their screening in vitro against S. aureus and E. coli were found to passes considerable activity. |
| | Studies in Sulphonamides Part VIII
Author : Mohan, Chandra;Saharia, G.S. ;Sharma, H.R.
Source : Defence Science Journal ; Vol:25(2) ; 1975 ; pp 55-58
Subject : 57.089 Biomedical Sciences ;577 Biochemistry;61 Medical Sciences;615 Pharmacology
Keywords : Sulphonamides;Antibacterial properties
Abstract : 1-Ary1-3-methypropane-1,3-diones, viz.,1-(4/Sup1 chloropheny1),1-4'-bromopheny1)-1-(4'-chloro-3'-methy1-pheny1)-and -bipheny1-3-methy1Propane-1,3-dions have been synthesised and coupled with different dinzotises sulphonamied, bases in presence of sodium acetate to furnish the respective 1-ary1-3- methy1-2(subsituted sulphonamidobe-nzeneazo propane-1,3-diones.All these azo compounds have been tested in vitro for their antibacterial properties against S. aureus and E. coli and majority of these are found active against S. aureus. |
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