| || Chemistry and Toxicology of Sulphur Mustard: A Review
Author : Swamy, R.V. ;Sugendran, K.;Ganesan, K.;Malhotra, R.C.
Source : Defence Science Journal ; Vol:49(2) ; 1999 ; pp 97-116
Subject : 623.459 Chemical Weapons
Keywords : Chemical warfare agent ;Sulphur mustard;Bis2 chloroethyl sulphide
Abstract : Bis (2-chloroethyl) sulphide commonly known as sulphur mustard (SM) is highly reactive bifunctional compound, documented as antimitotic, mutagenic, carcinogenic, teratogenic and cytotoxic agent. It is a powerful vesicant and has been employed as a chemical warfare agent. Skin, eyes and respiratory tract are the principal target organs and the deoxyribose nucleic acid (DNA) is the most important molecular target of SM toxicity. There is no specific antidote for SM injury .Treatment to SM toxicity is symptomatic.