 | Azo compounds |
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 | Studies in Sulphonamides Part VI
Author : Sharma, H.R. ;Saharia, G.S.
Source : Defence Science Journal ; Vol:22(2) ; 1972 ; pp 139-142
Subject : 54 Chemistry;547 Organic Chemistry
Keywords : Pharmacological properties ;Azo compounds;Diazotised sulphonamide
Abstract : Five different 1:3-diaryl propane-1:3-diones, 1-(m-nitrophenyl)-3-phenyl-, 1-(m-nitrophenyl)-3-(p-methoxyphenyl)-, 1-(p-methoxyphenyl)-3-(p-bromophenyl)-and 1-(pmethoxyphenyl)-3-(p-chorophenyl) propane-1:3-diones have been synthesised and coupled with eight different diazotised sulphonamide bases to give 1:3-diary 1-2(substituted sulphonamidobenzeneazo) propane-1:3-dicnes. The pharmacological properties of all these azo-compounds have been studied in vitro by the cup-plate method. |
| | Studies in Heterocyclic Compounds Part VIII
Author : Kabra, Ajaya ;Mutreja, H.C.;Saharia, G.S.;Sharma, H.R.
Source : Defence Science Journal ; Vol:26(2) ; 1976 ; pp 75-80
Subject : 547 Organic Chemistry;577 Biochemistry;579 MicroBiology
Keywords : Azo compounds;TLC ;Heterocyclic Compounds
Abstract : Different azo compounds, 1-(m-nitrophenyl)-3-(p-bromophenyl)-and 1-(m-nitrophenyl) 3-(p-chlorophenyl)-2-(substituted sulphonamidobenzeneazo) propane-1,3-dinoes on condensation with hydrazine hydrate (100%), phenylhydrazine, p-nitrophenyllhydrazine and benzoylhydrazine yield the corresponding 1-simple/substituted-3-(m-nitrophenyl)-5-(p-bromo chlorophenyl)-4-(substituted sulphonamidobenzeneazo) pyrazoles. The homogeneity and purity of these was confirmed by TLC and these on screening in vitro against S. aureus and E. coli were found to exhibit antibacterial activity. |
| | Studies in Sulphonamides Part XII
Author : Sharma, H.R. ;Saharia, G.S.;Mutreja, H.C.
Source : Defence Science Journal ; Vol:30(1) ; 1980 ; pp 45-50
Subject : 54 Chemistry;547 Organic Chemistry
Keywords : Azo compounds ;Diazotised sulphonamide;3 diones
Abstract : Four new 1, 3-diarylpropane-1, 3-diones, 1-(m/p-nitrophenyl)-3-(p-ethylphenyl)-and 1-(m/p-nitrophenyl)-3-(p-ehoxyphenyl) propane-1, 3-diones have been synthesised and coupled with a number of diazotised sulphonamide bases to yield the corresponding 1, 3-diaryl-2-(N-substituted p-sulphamylbenzeneazo) propane-1, 3-diones. These azo-compounds have been screened in vitro for their antibacterial properties against S. aureus, E. coli and P. pyocyanea. |
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