 | Pharmacological properties |
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 | Studies in Sulphonamides Part VI
Author : Sharma, H.R. ;Saharia, G.S.
Source : Defence Science Journal ; Vol:22(2) ; 1972 ; pp 139-142
Subject : 54 Chemistry;547 Organic Chemistry
Keywords : Pharmacological properties ;Azo compounds;Diazotised sulphonamide
Abstract : Five different 1:3-diaryl propane-1:3-diones, 1-(m-nitrophenyl)-3-phenyl-, 1-(m-nitrophenyl)-3-(p-methoxyphenyl)-, 1-(p-methoxyphenyl)-3-(p-bromophenyl)-and 1-(pmethoxyphenyl)-3-(p-chorophenyl) propane-1:3-diones have been synthesised and coupled with eight different diazotised sulphonamide bases to give 1:3-diary 1-2(substituted sulphonamidobenzeneazo) propane-1:3-dicnes. The pharmacological properties of all these azo-compounds have been studied in vitro by the cup-plate method. |
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