| || Studies in Heterocyclic Compounds Part XXXIII : Synthesis and in vitro screening of some 1 3 diaryl 5 arylazo N substituted p sulphmulbenzeneazo dihydro 2 thioxo 4 6 1H 5H pyrimidinedioes
Author : Sharma, H.R. ;Saharia, G.S.;Nigam, S.C.
Source : Defence Science Journal ; Vol:31(1) ; 1981 ; pp 15-22
Subject : 54 Chemistry;547 Organic Chemistry
Keywords : Diazotised sample ;Sulphonamide bases
Abstract : 1-Phenyl-3-(p-methoxyphenyl)- and 1,3-di(p-methoxyphenyl) dihydro-2-thioxo-4,6 (1H, 5H)-pyrimidinediones have been synthesised and coupled with different diazotised simple and sulphonamide bases to furnish the corresponding 5-(arylazo/N- substituted p-sulphamylbenezeneazo)dihydro-2-thioxo-4, 6(1H, 5H)-pyrimidinediones. On in vitro screening these were found to exhibit considerable activity against a number of micro-organisms.