| || Drug Xenobiotic Metabolism Disposition and Toxicity in Malnutrition
Author : krishnaswamy, Kamala
Source : Defence Science Journal ; Vol:37(2) ; 1987 ; pp 133-142
Subject : 615.9 Toxicology;615 Pharmacology
Keywords : Bio transformation ;Protein binding distribution
Abstract : "The role of malnutrition and diet in general on bioprocess, which govern the fate of drug/xenobiotic in the body only just beginning to be understood. Absorption, protein binding distribution, bio-transformation and renal elimination of xenobiotics/drugs are all affected by altered states of nutrition. As such, evaluation of nutritional status is highly relevant prior to prolonged drug thereby especially with drugs having narrow safety margin. "