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 | Drug Xenobiotic Metabolism Disposition and Toxicity in Malnutrition Author : krishnaswamy, Kamala Source : Defence Science Journal ; Vol:37(2) ; 1987 ; pp 133-142 Subject : 615.9 Toxicology;615 Pharmacology Keywords : Bio transformation ;Protein binding distribution Abstract : "The role of malnutrition and diet in general on bioprocess, which govern the fate of drug/xenobiotic in the body only just beginning to be understood. Absorption, protein binding distribution, bio-transformation and renal elimination of xenobiotics/drugs are all affected by altered states of nutrition. As such, evaluation of nutritional status is highly relevant prior to prolonged drug thereby especially with drugs having narrow safety margin. " |
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